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We appreciate the funding support of NIH-NHLBI (2R15HL143545-02)

Introduction The term autophagy originates from Greek and means self-devouring. The Belgian scientist Christian Ren de Duve, who won the Nobel Prize in Physiology or Medicine for his identification of lysosomes and peroxisomes, first proposed the concept of autophagy. In eukaryotic cells, autophagy refers to the fact that under conditions of stress such as nutrient starvation, damaged proteins and other components within the cell body are translocated into the lysosome and then degraded into small compounds for reuse, which sustains cellular homeostasis

In pursuit of a fairer complexion, individuals may undergo several weeks to months of glutathione treatment sessions